1. Age of the woman undergoing treatment
Getting pregnant after 30 is difficult because people’s fecundity slowly declines after that age. Women who are older are more likely to develop health conditions that affect their fertility, such as uterine fibroids, sexually transmitted diseases, and endometriosis.
2. Quality and quantity of eggs
The quality of your eggs also gets affected with age, so it is very important that you have a sufficient quantity and quality of eggs after you have been aging.
- Patients who have up to four eggs are low responders.
- Patients who have five to nine eggs are suboptimal responders.
- Patients who have nine to fifteen eggs are normal responders.
- Patients who have fifteen to twenty eggs are okay in this region.
The number of eggs needed for one IVF cycle is between 13 and 15. As with having more embryos, you will probably be able to have more children in the future.
3. Quality of the sperm
Semen analysis is the most important test to check the quality of sperm. IVF requires at least 10 x 10(6) sperm/mL, of which 30% must be motile and 15% must be progressive.
4. Endometrial lining thickness
The goal of IVF is to achieve pregnancy through two important steps. First, you need good-quality embryos that can give life, and second, you need the place where that embryo will rest—your uterus. Even if you have the highest-quality embryos available, achieving a normal individual pregnancy is extremely difficult. This is why the thickness of the endometrial lining is so important.
5. Hematological factors
- Hereditary Thrombophilias
- Factor V Leiden
- F II Mutation
- MTHFR Mutation
- Protein C/S Deficiency
- Antithrombin III Deficiency
6. Immunological factor
The immune system is also involved in the formation of eggs. If there is an issue with an autoimmune disease, that will affect the formation of the eggs.
7. Lifestyle factors (e.g. diet, exercise, body mass index, stress)
Having a poor diet, not exercising regularly, having a high body mass index, and being under stress also affect the success rate of IVF. You can ask your healthcare provider to structure your diet plan. Do exercise for at least 30 minutes, five days a week. If you are overweight, keep your BMI between 20 and 24.9 kg/m2, and absolutely manage your stress.
8. Previous fertility treatments or surgeries
Previous fertility treatments or surgeries can also affect your IVF treatment success rate.
9. Good IVF laboratory
Another important factor is a good IVF laboratory, and couples frequently make mistakes in this area. A good IVF lab with the latest technology and experienced embryologists can provide a better quality of embryo safety for all procedures.