Role of Lonopin Injection in IVF


Lonopin is an injection used during the IVF process. This injection is not required for all patients; it is recommended for those who have a history of miscarriage. When women who have had miscarriages in the past take Lonopin during pregnancy, it prevents the formation of blood clots and prevents miscarriage.

What is Lonopin Injection?

Lonopin Injection is a prescription anticoagulant. The use of this injection helps treat and prevent dangerous blood clots. The pharmaceutical composition of this medication is enoxaparin.

This injection prevents not only the existing clot from growing bigger but also the formation of any new clots. This prevents clots from forming in your veins. The condition is also known as pulmonary embolism or thrombosis.

Lonopin injections are given by a doctor or nurse. This injection is given into the thick tissue under your skin. Most of the time, this doctor gives this injection once a day, but in some cases, he may give it twice as well. To maintain the blood level, he gives it at the same time every day.

Role of lonopin Injection in the IVF Process

Your doctor may recommend that you take Lonopin for at least five months if you have had multiple miscarriages, IVF failures, or recurrent fetal losses. There are no side effects for the baby, even though it is painful.

In the case of a high-risk pregnancy, your doctor will give you this injection as a precaution. Doctors say it helps grow the placenta or uterus. Therefore, even though it is painful, it is necessary for the baby.


When to Stop Lonopin Injection During Pregnancy

The use of Lonopin for at least five months after pregnancy seems necessary if she has experienced repeated miscarriages, repeated fetal deaths, or repeated IVF failures. It is better to take this injection daily.


The dosage of this injection depends on the body weight, which is shown in the table below.

Body WeightDose
< 50 KG20 MG SC Daily
50-90 KG40 MG SC Daily
> 90 KG40 MG BD

Common side effect

During pregnancy, lonopin does not cross the placenta, so it has no side effects on the fetus. The common side effects of lonopin, can include headache, decreased blood platelets, hot flashes, Increased liver enzymes, mood changes, difficulty sleeping, itching or swelling at the injection area.

These side effects are generally mild and tend to go away after a few days or weeks.If you experience any severe or persistent side effects while taking lonopin, you should talk to your doctor as soon as possible.


The fetus may be affected by oral formulations of anticoagulants such as warfarin and acenocoumarol, which can lead to abortion. That’s why doctors always recommend injections instead of tablets.

During pregnancy, women who are at high risk for blood clot formation should also take the tablet Ecosprin along with the Lonopin injection.

No, you should not consume alcohol/smoking. Although its interaction with alcohol is unknown, you should still avoid it.


Lonopin injections play a very important role in your IVF pregnancy. To ensure the best results, you should take the injection daily as prescribed by your doctor and also try to take it at the same time every day.

This article is intended for people who have undergone IVF treatment, but it may be helpful to others as well. I hope you will share it with them.

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