What Happens After Blastocyst Transfer?


After a blastocyst transfer, which usually occurs on days 5 or 6 after egg retrieval during in vitro fertilisation (IVF), the embryo will begin to implant into the lining of the uterus. A blastocyst implants into the uterine lining and invades the endometrium during the implant process.

Once the embryo has been successfully implanted, it will begin to develop and grow. Over the next several days and weeks, the embryo will continue to develop, and the placenta will form to support the growing fetus.

It’s important to note that every woman’s experience with IVF is different, and not all embryos will implant successfully. If implantation is successful, the woman will become pregnant and will need to continue monitoring her pregnancy with regular checkups and appointments with her doctor.

What Happens After Blastocyst Transfer

What happens after blastocyst transfer?

After the blastocyst transfer, which typically occurs on days 5 or 6 after egg retrieval, the embryo will begin to implant into the lining of the uterus. Here’s what typically happens after the transfer:

Day 1: During day one, the blastocyst continues to hatch and begin attaching to the uterine wall.

Day 2: The blastocyst will begin to burrow deeper into the uterine lining, and implantation will begin.

Day 3: Work continues to implant the blastocyst into the uterus. The cells of the blastocyst will begin to differentiate into the placenta and the embryo.

Day 4: Implantation of the blastocyst continues, and the placenta begins to form.

Day 5–6: The blastocyst is fully implanted into the uterine lining, and the placenta is almost completely formed. The embryo begins to develop rapidly and starts to produce human chorionic gonadotropin (hCG), which is the hormone that pregnancy tests detect.

Day 7–10: The embryo continues to develop, and hCG levels in the mother’s blood increase, confirming the pregnancy. The embryo begins to secrete a hormone called progesterone, which helps sustain the pregnancy.

Day 11–14: The embryo continues to grow and develop, and the placenta continues to form. To support the pregnancy, the mother’s body begins to produce more oestrogen and progesterone.

If the embryo implants successfully, a pregnancy will continue to develop. If the embryo does not implant, the woman’s period will start a few days later, and the cycle will be unsuccessful. It’s important to note that every woman’s experience with IVF is different, and not all embryos will implant successfully.

When to do a pregnancy test after blastocyst transfer

The timing of a pregnancy test after a blastocyst transfer can vary depending on the individual case and the preferences of the doctor. However, in general, most clinics will recommend waiting about 10–12 days after the blastocyst transfer before taking a pregnancy test. A pregnancy test detects human chorionic gonadotropin (hCG), a hormone produced by embryos during this waiting period.

Taking a pregnancy test too early can result in a false negative result, as the levels of hCG may not yet be high enough to be detected by the test. It’s important to follow your doctor’s recommendations and guidelines for testing and to avoid taking an at-home pregnancy test too early or too often, as this can lead to unnecessary stress and anxiety.

How do you feel after the transfer?

After a blastocyst transfer, many women may experience some physical and emotional symptoms, although everyone’s experience is different. Some common physical symptoms that women may experience after a blastocyst transfer include:

  1. Cramping: Mild to moderate cramping is common after the transfer and is typically caused by the uterus contracting as it adjusts to the presence of the embryo.
  2. Spotting or light bleeding: Some women may experience light spotting or bleeding after the transfer, which is typically caused by irritation of the uterine lining during the transfer.
  3. Bloating and discomfort: Many women may feel bloated and uncomfortable after the transfer, which is caused by the hormone medication used during the IVF process.
  4. Fatigue: The hormonal changes and stress of the IVF process can cause fatigue and exhaustion.

In addition to physical symptoms, women may also experience emotional symptoms such as anxiety, excitement, and uncertainty. It’s important to take care of yourself after the transfer and to reach out to your doctor if you have any concerns or questions. They can provide guidance and support throughout the IVF process.

Improve your chances of success after blastocyst transfer.

Here are some ways to improve your chances of success after blastocyst transfer:

  1. Follow your doctor’s instructions: It’s essential to follow your doctor’s instructions carefully, including any medication or supplement prescribed to you. Your doctor will provide you with specific instructions on when and how to take these medications to maximise your chances of success.
  2. Maintain a healthy lifestyle: Maintaining a healthy lifestyle is critical when trying to conceive.  This includes eating a healthy diet, getting enough exercise, and avoiding smoking, alcohol, and caffeine.
  3. Reduce stress: Reducing stress is essential during the IVF process, as stress can have a negative impact on your reproductive system. Consider practising relaxation techniques, such as meditation or yoga, to help manage stress levels.
  4. Get enough rest. It’s crucial to get enough rest during the IVF process. Consider taking time off work or reducing your workload to reduce stress and allow your body to rest.
  5. Stay strong and positive. It’s important to stay positive and hopeful throughout the process. Talk to your partner or a trusted friend about your feelings and concerns.

Factors affecting successful implantation

There are several factors that can affect the success of implantation after blastocyst transfer. These include:

  • Age: As a woman ages, the quality of her eggs decreases, which can make it more difficult for an embryo to implant successfully.
  • Uterine health: The health and thickness of the uterine lining can affect the ability of the embryo to implant. Conditions such as endometriosis, fibroids, and polyps can also impact implantation.
  • Hormone levels: Implantation is regulated by a complex interplay of hormones, including estrogen, progesterone, and human chorionic gonadotropin (hCG). Imbalances or deficiencies in these hormones can impact implantation.
  • Lifestyle factors: Smoking, excessive alcohol consumption, and a high body mass index (BMI) can all negatively impact fertility and implantation.
  • Genetic factors: Genetic abnormalities in the embryo can also impact implantation and pregnancy outcomes.
  • Previous fertility treatments: Previous fertility treatments or surgeries can impact the health and quality of the uterus, making it more difficult for an embryo to implant successfully.
  • Stress: High levels of stress and anxiety can impact the hormonal balance and make it more difficult for an embryo to implant.

Follow-up Care

After a blastocyst transfer, it’s important to follow up with your doctor to monitor the success of the implantation and pregnancy. The following are some aspects of follow-up care:

  1. Pregnancy testing: Your doctor will schedule a blood test to check for the presence of human chorionic gonadotropin (hCG), which indicates pregnancy. They may also schedule a series of ultrasounds to monitor the development and growth of the embryo.
  2. Medications: Your doctor may prescribe medications such as progesterone to help support the pregnancy and prevent miscarriage.
  3. Lifestyle modifications: Your doctor may recommend lifestyle modifications such as avoiding alcohol and tobacco, eating a healthy diet, and avoiding strenuous exercise to support the health of the embryo and pregnancy.
  4. Emotional support: The IVF process can be emotionally challenging, and it’s important to seek emotional support from your doctor, friends, and family members as needed.
  5. Complications: In some cases, complications such as ectopic pregnancy, miscarriage, or preterm labor may occur. It’s important to seek medical attention if you experience any symptoms such as vaginal bleeding, cramping, or severe abdominal pain.

By following up with your doctor and following their recommendations, you can optimize your chances of a successful pregnancy after a blastocyst transfer.


In conclusion, after a blastocyst transfer, the embryo will begin to implant into the lining of the uterus and develop into a fetus.  The process of implantation and development is complex and varies for each woman, and not all embryos will successfully implant.

It is important for women who have undergone IVF to monitor their pregnancy closely with regular checkups and appointments with their doctor. As a language model, I am here to provide information and assistance on a wide range of topics, including IVF and pregnancy.

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1. How long after blastocyst transfer does implantation occur?

Implantation after blastocyst transfer usually occurs within 1-2 days after the transfer. The blastocyst, which is the stage of the embryo at the time of transfer, will begin to attach itself to the lining of the uterus on the first day after transfer.

On the second day, the blastocyst will start to burrow deeper into the uterine lining, which is the process of implantation. Implantation is a crucial step in the development of a pregnancy and marks the beginning of the formation of the placenta, which provides oxygen and nutrients to the growing fetus.

However, it’s important to note that not all embryos will successfully implant, and the timing of implantation can vary for each woman.  If you have any concerns about your IVF cycle or implantation, it’s best to speak with your doctor for guidance and support.

2. What is the success rate of blastocyst transfers?

The success rate of blastocyst transfers depends on a variety of factors, including the age and health of the woman, the quality of the embryos, and the fertility clinic performing the procedure.

Generally speaking, blastocyst transfers have a higher success rate than earlier-stage embryo transfers, such as those done on day 3 after fertilization.

According to the Society for Assisted Reproductive Technology (SART), the success rate for blastocyst transfers in women under 35 is around 55–65%, and the success rate drops as the woman’s age increases.

3. How long does it typically take for new embryos to implant?

After an embryo transfer, the implantation process typically takes place within five to seven days. However, the timing of implantation can vary depending on various factors, such as the quality of the embryo, the receptivity of the uterus, and the timing of the embryo transfer.

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